abstract：:Inherited cerebellar ataxias constitute a complicated and heterogeneous group of neurodegenerative disorders affecting the cerebellum and/or spinocerebellar tract, spinal cord and peripheral nerves. A peripheral neuropathy is frequently seen in inherited cerebellar ataxias although it rarely reveals the disease. Moreo...

journal_title：Revue neurologique

authors： Anheim M,Tranchant C

更新日期：2011-01-01 00:00:00

abstract：:Botulinum toxin type A (BTX-A) is a potent neurotoxin that blocks acetylcholine release from presynaptic nerve terminals by cleaving the SNARE complex. BTX-A has been reported to have analgesic effects independent of its action on muscle tone. The most robust results have been observed in patients with neuropathic pai...

journal_title：Revue neurologique

authors： Ranoux D

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Demyelinating diseases presenting with a tumefactive demyelinating lesion (TDL) raise questions about classification, diagnosis, prognosis, and treatment. Their long-term course is not well described in literature. PATIENTS/METHODS:In a retrospective study, we describe the main characteristics of 29 patient...

journal_title：Revue neurologique

authors： Launay M,Lebrun C,Giordana E,Chanalet S,Thomas P

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:In genetic diseases, association between retinal and muscular involvement is uncommon, quite specific and frequently allows the diagnosis. In this context, three types of retinal involvement have been described: retinitis pigmentosa (RP), pattern retinal dystrophy (PRD) and exudative retinitis resembling C...

journal_title：Revue neurologique

authors： Sacconi S,Baillif-Gostoli S,Desnuelle C

更新日期：2010-12-01 00:00:00

abstract：:Myasthenia gravis is a rare, auto-immune disorder of the neuromuscular junction. Onset signs frequently involve ocular muscles, accounting for ptosis and/or diplopia in more than 75% of cases. Among the cases with purely ocular muscle involvement, less than one half will never progress towards a more general form of m...

journal_title：Revue neurologique

authors： Stojkovic T,Béhin A

更新日期：2010-12-01 00:00:00

abstract：:In sub-Saharan Africa, stroke is likely to present an increasingly important public health problem with a larger relative share of overall morbidity and mortality. Overall, sub-Saharan Health Care is characterized by a lack of human resources, lack of facilities for special investigations, and especially an absence of...

journal_title：Revue neurologique

authors： Adoukonou TA,Vallat JM,Joubert J,Macian F,Kabore R,Magy L,Houinato D,Preux PM

更新日期：2010-11-01 00:00:00

abstract：INTRODUCTION:Health related quality of life (HRQOL) is often affected in multiple sclerosis (MS). Nevertheless, to our knowledge, there is no longitudinal study in the literature about the correlation between MRI parameters and HRQOL in MS patients. METHODS:We included 28 patients with clinically definite relapsing re...

journal_title：Revue neurologique

authors： Cohen M,Lebrun C,Aufauvre D,Chanalet S,Filleau-Bertogliatti C,Camu W,Thomas P,Malandain G,Clavelou P

更新日期：2010-11-01 00:00:00

abstract：:Rapid eye movement (REM) sleep behavior disorder (RBD) is characterized by violent, or potentially violent, movements during REM sleep, corresponding to enacted dreams. During sleep monitoring, there is a partial or total loss of the normal muscle atonia during REM sleep. REM sleep behavior disorder predominantly affe...

journal_title：Revue neurologique

authors： Arnulf I

更新日期：2010-10-01 00:00:00

abstract：:Dysarthria refers to a collective name for a group of neurologic motor speech disorders, resulting from central and/or peripheral nervous system abnormalities. Speech alteration in Parkinson's disease, so-called hypokinetic dysarthria, presents with prosodic insufficiency, related to a monotony of pitch and intensity,...

journal_title：Revue neurologique

authors： Pinto S,Ghio A,Teston B,Viallet F

更新日期：2010-10-01 00:00:00

abstract：:It has become increasingly evident over the past years that the pathological process in Parkinson's disease extends well beyond the substantia nigra and involves non-dopaminergic neurotransmitter systems that mediate motor and non-motor symptoms. In this article, both the pathophysiology and the pharmacological manage...

journal_title：Revue neurologique

authors： Derkinderen P

更新日期：2010-10-01 00:00:00

abstract：:The diagnosis of Parkinson's disease (PD) requires ruling out other causes of parkinsonism. Among various "other" causes of parkinsonism, neurodegenerative causes or "atypical parkinsonism" are the most difficult to diagnose. Most common diseases are "synucleinopathies": multiple system atrophy and dementia with Lewy ...

journal_title：Revue neurologique

authors： Tison F

更新日期：2010-10-01 00:00:00

abstract：INTRODUCTION:Patient H.M.'s recent death provides the opportunity to highlight the importance of his contribution to a better understanding of the anterograde amnesic syndrome. The thorough study of this patient over five decades largely contributed to shape the unitary model of declarative memory. This model holds tha...

journal_title：Revue neurologique

authors： Barbeau EJ,Puel M,Pariente J

更新日期：2010-08-01 00:00:00

abstract：INTRODUCTION:Neurological involvement associated with copper deficiency has been reported recently in humans and may be under-recognized. CASE REPORT:A 65-year-old patient, with past history of gastrectomy 40 years earlier, developed a myelodysplastic syndrome and then subacute onset of progressive gait ataxia and par...

journal_title：Revue neurologique

authors： Bellance R,Edimo Nana M,Kone M,Deschamps R,Parry A,Signate A,Panelatti G,Smadja D

更新日期：2010-08-01 00:00:00

abstract：:BAC 40 is a "composite" battery of psychometric tests useful for the diagnosis of Alzheimer's dementia. It was elaborated using the modified Mini-Mental Status (MMS). The advantage is to establish a diagnosis in less than 20 minutes, exploring all the sectors of cognitive life. This tool was validated in a control pop...

journal_title：Revue neurologique

authors： Guard O

更新日期：2010-06-01 00:00:00

abstract：INTRODUCTION:The Rapid BAttery of Denomination (BARD) is a short 10-item naming test derived from the 60-item Boston Naming Test. It is easily performed in less than 15 seconds by normal controls independently of age, gender and education (Croisile, 2005,2007,2008). Our aim was to evaluate the BARD in various condition...

journal_title：Revue neurologique

authors： Croisile B,Astier JL,Beaumont C,Mollion H

更新日期：2010-06-01 00:00:00

abstract：INTRODUCTION:The first decline in cognitive performance in Alzheimer's disease can appear when assessing semantic memory and can be detected long before the typical symptoms of Alzheimer's disease (AD), appearing with Mild Cognitive Impairment (MCI). PATIENTS AND METHOD:We propose the French version of the New Words I...

journal_title：Revue neurologique

authors： Thomas-Antérion C,Borg C,Basaglia-Pappas S,Laroche L,Minvielle B,Bedoin N

更新日期：2010-04-01 00:00:00

abstract：INTRODUCTION:Multiple acyl-CoA dehydrogenase deficiency (MADD) is a rare genetic disease involving fatty acid oxidation. It is due to the deficiency of one of the two electron transporters: electron transfer flavoprotein (ETF) or electron transfer flavoprotein ubiquinone oxydoreductase (ETF-QO). Symptoms begin more oft...

journal_title：Revue neurologique

authors： Maillart E,Acquaviva-Bourdain C,Rigal O,Brivet M,Jardel C,Lombès A,Eymard B,Vianey-Saban C,Laforêt P

更新日期：2010-03-01 00:00:00

abstract：:From one year of age, gait and balance disorders are frequent complaints in neurology. During the first year following the acquisition of independent walking, most of the gait, such as transition from digitigrade to plantigrade locomotion, parameters are well-established in children. Nevertheless, bipedal locomotion m...

journal_title：Revue neurologique

authors： Assaiante C,Chabrol B

更新日期：2010-02-01 00:00:00

abstract：:In Huntington's disease (HD), perturbed locomotion occurs early in the course of the disease and presents numerous clinical features. The gait disorders in HD might best be defined as a timing disorder; however, hypokinesia (i.e. a decrease in stride length) also plays an important role in disturbed locomotion as HD p...

journal_title：Revue neurologique

authors： Delval A,Krystkowiak P

更新日期：2010-02-01 00:00:00

abstract：:The low cerebral bioavailability of various drugs is a limiting factor in the treatment of neurological diseases. The restricted penetration of active compounds into the brain is the result of the same mechanisms that are central to the maintenance of brain extracellular fluid homeostasis, in particular from the stric...

journal_title：Revue neurologique

authors： Ghersi-Egea JF,Mönkkönen KS,Schmitt C,Honnorat J,Fèvre-Montange M,Strazielle N

更新日期：2009-12-01 00:00:00

abstract：INTRODUCTION:Tracking can be proposed for subjects with prodromal sates of Alzheimer disease (AD) or people with mild cognitive impairment (MCI) at risk to develop dementia who present a memory complaint. PATIENTS AND METHODS:We present a cohort of 100 subjects who attended a French memory unit with a diagnostic of MC...

journal_title：Revue neurologique

authors： Dionet E,Fédérico D,Foyatier-Michel N,Dirson S,Cadet L,Thomas-Antérion C

更新日期：2009-12-01 00:00:00

abstract：:Viruses that infect the nervous system may cause acute, chronic or latent infections. Despite the so-called immunoprivileged status of the nervous system, immunosurveillance plays an important role in the fate of viral infection of the brain. Herpes simplex virus 1 (HSV-1) persists in the nervous system for the life o...

journal_title：Revue neurologique

authors： Lafon M

更新日期：2009-12-01 00:00:00

abstract：:The involvement of a viral infection in the physiopathology of multiple sclerosis has been said to cause certain viruses to target the central nervous system and induce neuroinflammation leading to cell dysfunction, as seen, for example, by demyelination or neuronal death. The most recent results of the literature hav...

journal_title：Revue neurologique

authors： Giraudon P,Bernard A

更新日期：2009-10-01 00:00:00

abstract：:There is no one ligand for visualising "the epileptogenic zone". Several PET ligands, however, can help by noninvasively or minimally invasively refining hypotheses regarding its location. Their relative merits depend not only on local availability and expertise, but also on epilepsy syndrome and overall diagnostic ca...

journal_title：Revue neurologique

authors： Hammers A

更新日期：2009-10-01 00:00:00

abstract：INTRODUCTION:When advanced Parkinson's disease (PD) patients experience motor complications (fluctuations and dyskinesias) despite standard oral treatment, two treatment options are available: deep brain stimulation and subcutaneous apomorphine infusion with respects of indications for each strategy. Continuous intradu...

journal_title：Revue neurologique

authors： Annic A,Devos D,Seguy D,Dujardin K,Destée A,Defebvre L

更新日期：2009-08-01 00:00:00

abstract：INTRODUCTION:Erdheim-Chester disease (ECD) is a rare non-langerhans cell histiocytosis of unknown etiology. It is a multi-systematic xanthogranulomatous infiltration with almost constant bone involvement; the neurological manifestations are not specific and occur in 15-20% of cases. METHODS:We report the case of a 59-...

journal_title：Revue neurologique

authors： Amezyane T,Abouzahir A,Bassou D,Zoubeir Y,Hammi S,Mahassin F,Ohayon V,Archane MI

更新日期：2009-06-01 00:00:00

abstract：INTRODUCTION:Parry-Romberg syndrome is a rare entity of unknown etiology, characterized by hemifacial or hemibody atrophy affecting subcutaneous tissues. Its main clinical manifestations are neurological, ocular and dermatological. Paroxysmal kinesigenic dyskinesia (PKD) is characterized by brief episodes of choreic/dy...

journal_title：Revue neurologique

authors： Mrabet Khiari H,Masmoudi S,Mrabet A

更新日期：2009-05-01 00:00:00

abstract：:The French system of law concerning marketing authorisations for blood-derived medicines is currently being contested by foreign laboratories claiming that our legislation limits the importation of medicines developed from remunerated blood and plasma donation. This criticism is not entirely founded; nonetheless, it w...

journal_title：Revue neurologique

authors： Pellet R

更新日期：2009-05-01 00:00:00

abstract：:The mechanisms that induce epileptic activity and make it durable, leading to status epilepticus (SE), are poorly known. They probably result from an imbalance between the activating systems of neuronal depolarisation (excitatory amino acids release with postsynaptic N-methyl-d-aspartate [NMDA] receptor activation, sp...

journal_title：Revue neurologique

authors： Engrand N,Crespel A

更新日期：2009-04-01 00:00:00

abstract：INTRODUCTION:Posterior cortical atrophy (PCA) is a clinically and radiologically defined syndrome, in which predominant symptoms focus on higher visual dysfunction with progressive course and association with cortical atrophy or hypometabolism that predominates in the posterior part of the hemispheres. Homonymous hemia...

journal_title：Revue neurologique

authors： Formaglio M,Krolak-Salmon P,Tilikete C,Bernard M,Croisile B,Vighetto A

更新日期：2009-03-01 00:00:00

abstract：:Most multiple sclerosis (MS) patients experience some bladder, sexual, and/or bowel dysfunction during the course of the disease, which has been closely associated with the quality-of-life scores, including in patients with otherwise low disability. This underlines the need for identifying and treating these problems....

journal_title：Revue neurologique

authors： Donzé C,Hautecoeur P

更新日期：2009-03-01 00:00:00

abstract：:Thymolipomas are rare, often asymptomatic benign tumors; their revelation by myasthenia is exceptional. A 49-year-old patient with a one-year history of fluctuant muscular fatigability developed ptosis. Electromyography revealed a myasthenic neuromuscular block. The CT scan disclosed a thymic mass especially important...

journal_title：Revue neurologique

authors： Lakranbi M,Caidi M,Ouadnouni Y,Benosman A

更新日期：2009-03-01 00:00:00

abstract：:The purpose of the treatment of autoimmune myasthenia gravis is to directly improve neuromuscular transmission, and also to reduce the production or presence of the nicotinic acetylcholine receptor (achR). Acetylcholinesterase inhibitors are the first line treatment with the rapid onset of effect, for all types of mya...

journal_title：Revue neurologique

authors： Tranchant C

更新日期：2009-02-01 00:00:00

abstract：INTRODUCTION:An observation of limbic encephalitis associated with Hodgkin's disease is compared with rare cases of the literature. The clinical presentation was relapsing episodes of febrile cognitive disorders with confusion and meningitis, curable after treatment of Hodgkin's disease. Recent concepts on limbic encep...

journal_title：Revue neurologique

authors： Serratrice J,Amri AB,Bouabdallah R,Ceccaldi M,Weiller PJ

更新日期：2009-01-01 00:00:00

abstract：:Different sets of criteria are currently used for the diagnosis of multiple sclerosis (MS). Some are based on clinical features, while others are related to imaging findings. Among the image processing systems, specific criteria include spatial dissemination of lesions in one image or their temporal dissemination in i...

journal_title：Revue neurologique

authors： Souplet JC,Lebrun C,Chanalet S,Ayache N,Malandain G

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Celiac disease (CD) may be complicated by an enteropathy associated T-cell lymphoma (EATL), but lymphomatous dissemination outside the gastrointestinal tract is uncommon especially to the peripheral nervous sytem. OBSERVATION:We report a 54-year-old CD patient with EATL revealed by subacute polyradiculopa...

journal_title：Revue neurologique

authors： Jousserand G,Poujois A,Antoine JC,Camdessanché JP

更新日期：2009-01-01 00:00:00

abstract：:The diagnostic process of sensory-motor neuropathies is difficult. Atypical variants and rare etiologies also contribute to delay the diagnosis. We report the case of a 70-year-old woman with slowly progressive asymmetric axonal sensory-motor neuropathy. Leprosy was identified after an eight-year delay. Nerve biopsy w...

journal_title：Revue neurologique

authors： Gabelle A,Vallat JM,Flageul B,Andre P,Camu W

更新日期：2008-11-01 00:00:00

abstract：INTRODUCTION:Multiple sclerosis is a chronic progressive neurological disorder. For this reason, the clinician needs to have access to treatments that are effective and well-tolerated over decades. However, in the absence of long-term controlled clinical trials, it is difficult to assess the long-term benefit provided ...

journal_title：Revue neurologique

authors： Brochet B

更新日期：2008-11-01 00:00:00

abstract：:Silent brain infarcts and leucoaraiosis are frequently observed in patients with transient ischemic attack (TIA) and ischemic stroke. Patients with silent brain infarcts and leucoaraiosis at baseline are a high-risk group with an increased long-term risk for recurrent stroke, cognitive decline, and dementia. Effects o...

journal_title：Revue neurologique

authors： Norrving B

更新日期：2008-10-01 00:00:00

abstract：:Central post-stroke pain (CPSP) is known since the famous Dejerine-Roussy syndrome and its description has not improved. The subject has however been revived over the last decade thanks to advances in central nervous system imaging with magnetic resonance imaging (MRI), the description of allodynia functional phenomen...

journal_title：Revue neurologique

authors： Demasles S,Peyron R,Garcia Larrea L,Laurent B

更新日期：2008-10-01 00:00:00